Article
Evidence of a target resistance to antivitamin K rodenticides in the roof rat Rattus rattus: identification and characterisation of a novel Y25F mutation in the Vkorc1 gene.
Pest management science - 1 Mar 2016
Goulois Joffrey, Chapuzet Audrey, Lambert Véronique, Chatron Nolan, Tchertanov Luba, Legros Lionel, Benoît Etienne, Lattard Virginie
Abstract excerpt
BACKGROUND: In spite of intensive use of bromadiolone, rodent control was inefficient on a farm infested by rats in Zaragoza, Spain. While metabolic resistance was previously described in this rodent species, the observation of a target resistance to antivitamin K rodenticides had been poorly documented in Rattus rattus. RESULTS: From rats trapped on the farm, cytochrome b and Vkorc1 genes were amplified by PCR...
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