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Large-scale identification of rodenticide resistance in Rattus norvegicus and Mus musculus in the Netherlands based on Vkorc1 codon 139 mutations.

Pest management science - 1 Mar 2023

Krijger Inge M, Strating Max, van Gent-Pelzer Marga, van der Lee Theo A J, Burt Sara A, Schroeten Fleur H, de Vries Robin, de Cock Marieke, Maas Miriam, Meerburg Bastiaan G

Abstract excerpt

BACKGROUND: Resistance to rodenticides has been reported globally and poses a considerable problem for efficacy in pest control. The most-documented resistance to rodenticides in commensal rodents is associated with mutations in the Vkorc1 gene, in particular in codon 139. Resistance to anticoagulant rodenticides has been reported in the Netherlands since 1989. A study from 2013 showed that 25% of 169 Norway rats...

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PMID: 36309944
DOI: 10.1002/ps.7261
PMCID: PMC10107327

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