Article
The impact of chronic Aflatoxin B1 exposure and p53 genotype on base excision repair in mouse lung and liver.
Mutation research - 1 Mar 2015
Mulder Jeanne E, Bondy Genevieve S, Mehta Rekha, Massey Thomas E
Abstract excerpt
Aflatoxin B1 (AFB1) is produced by species of Aspergillus, and is a known human carcinogen. AFB1-induced oxidative DNA damage, specifically 8-hydroxy-2-deoxyguanosine (8-OHdG) lesions, has been demonstrated in both animal models and in humans, and is repaired by base excision repair (BER). The tu...
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