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Article

Preservation of high glycolytic phenotype by establishing new acute lymphoblastic leukemia cell lines at physiologic oxygen concentration.

Experimental cell research - 15 May 2015

Sheard Michael A, Ghent Matthew V, Cabral Daniel J, Lee Joanne C, Khankaldyyan Vazgen, Ji Lingyun, Wu Samuel Q, Kang Min H, Sposto Richard, Asgharzadeh Shahab, Reynolds C Patrick

Abstract excerpt

Cancer cells typically exhibit increased glycolysis and decreased mitochondrial oxidative phosphorylation, and they continue to exhibit some elevation in glycolysis even under aerobic conditions. However, it is unclear whether cancer cell lines employ a high level of glycolysis comparable to that...

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Identifiers

PMID: 25845499
DOI: 10.1016/j.yexcr.2015.03.024
PMCID: PMC8219348

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25845499-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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