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Article

Immune system disturbances in schizophrenia.

Biological psychiatry - 15 Feb 2014

Horváth Szatmár, Mirnics Károly

Abstract excerpt

Epidemiological, genetic, transcriptome, postmortem, peripheral biomarker, and therapeutic studies of schizophrenia all point to a dysregulation of both innate and adaptive immune systems in the disease, and it is likely that these immune changes actively contribute to disease symptoms. Gene expression disturbances in the brain of subjects with schizophrenia show complex, region-specific changes with consistently...

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Identifiers

PMID: 23890736
DOI: 10.1016/j.biopsych.2013.06.010
PMCID: PMC3841236

Genes

IFITM3
SERPINA3

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