Article
The genetics of neuropsychiatric diseases: looking in and beyond the exome.
Annual review of neuroscience - 8 Jul 2015
Heinzen Erin L, Neale Benjamin M, Traynelis Stephen F, Allen Andrew S, Goldstein David B
Abstract excerpt
Next-generation sequencing, which allows genome-wide detection of rare and de novo mutations, is transforming neuropsychiatric disease genetics through identifying on an unprecedented scale genes and protein-coding mutations that confer risk. Although understanding how regulatory variants influence risk remains a challenge, we are likely transitioning into a phase of neuropsychiatric disease genetics in which the...
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