Article
FTO Gene Polymorphisms and Their Roles in Acromegaly.
International journal of molecular sciences - 30 Jun 2023
Jawiarczyk-Przybyłowska Aleksandra, Kuliczkowska-Płaksej Justyna, Kolačkov Katarzyna, Zembska Agnieszka, Halupczok-Żyła Jowita, Rolla Małgorzata, Miner Michał, Kałużny Marcin, Bolanowski Marek
Abstract excerpt
The major causes of both morbidity and mortality in patients with acromegaly are cardiovascular diseases (CVDs). The polymorphisms of the fat mass and obesity-associated gene (FTO) are associated with obesity, as well as with an increased risk of CVDs. The aim of the study was to determine the relationship of risk alleles of four FTO gene polymorphisms with selected parameters of lipid and glucose metabolism as...
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