Article
A MyD88-deficient mouse model reveals a role for Nramp1 in Campylobacter jejuni infection.
Infection and immunity - 1 Apr 2007
Watson Robert O, Novik Veronica, Hofreuter Dirk, Lara-Tejero María, Galán Jorge E
Abstract excerpt
Campylobacter jejuni is a major worldwide cause of enteric illnesses. Adult immunocompetent mice are not susceptible to C. jejuni infection. However, we show here that mice deficient in the adaptor protein myeloid differentiation factor 88 (MyD88), which is required for signaling through most Toll-like receptors, can be stably colonized by C. jejuni but not by isogenic derivatives carrying mutations in known...
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