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Article

The Helical Shape of Campylobacter jejuni Promotes In Vivo Pathogenesis by Aiding Transit through Intestinal Mucus and Colonization of Crypts.

Infection and immunity - 1 Dec 2016

Stahl Martin, Frirdich Emilisa, Vermeulen Jenny, Badayeva Yuliya, Li Xiaoxia, Vallance Bruce A, Gaynor Erin C

Abstract excerpt

Campylobacter jejuni is a helix-shaped enteric bacterial pathogen and a common cause of gastroenteritis. We recently developed a mouse model for this human pathogen utilizing the SIGIRR-deficient mouse strain, which exhibits significant intestinal inflammation in response to intestinal C. jejuni infection. In the current study, this mouse model was used to define whether C. jejuni's characteristic helical shape...

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Identifiers

PMID: 27647867
DOI: 10.1128/IAI.00751-16
PMCID: PMC5116718

Genes

SIGIRR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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