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Article

Phenotypic dysregulation of microglial activation in young offspring rats with maternal sleep deprivation-induced cognitive impairment.

Scientific reports - 1 Apr 2015

Zhao Qiuying, Xie Xiaofang, Fan Yonghua, Zhang Jinqiang, Jiang Wei, Wu Xiaohui, Yan Shuo, Chen Yubo, Peng Cheng, You Zili

Abstract excerpt

Despite the potential adverse effects of maternal sleep deprivation (MSD) on physiological and behavioral aspects of offspring, the mechanisms remain poorly understood. The present study was intended to investigate the roles of microglia on neurodevelopment and cognition in young offspring rats with prenatal sleep deprivation. Pregnant Wistar rats received 72 h sleep deprivation in the last trimester of...

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PMID: 25830666
DOI: 10.1038/srep09513
PMCID: PMC5381687

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