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Pregnancy-induced maternal microchimerism shapes neurodevelopment and behavior in mice

5 Aug 2022

Abstract excerpt

Life-long brain function and mental health are critically determined by developmental processes occurring before birth. During mammalian pregnancy, maternal cells are transferred to the fetus. They are referred to as maternal microchimeric cells (MMc). Among other organs, MMc seed into the fetal brain, where their function is unknown. Here, we show that, in the offspring's developing brain in mice, MMc express a...

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PMID: 35931682
DOI: 10.1038/s41467-022-32230-2

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