Article
Expected influence of linkage disequilibrium on genetic variance caused by dominance and epistasis on quantitative traits.
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie - 1 Apr 2015
Hill W G, Mäki-Tanila A
Abstract excerpt
Linkage disequilibrium (LD) influences the genetic variation in a quantitative trait contributed by two or more loci, with positive LD increasing the variance. The magnitude of LD also affects the relative magnitude of dominance and epistatic variation. We quantify the extent of the non-additive variance expected within populations, deriving analytical expressions for simple models and using numerical simulation...
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