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Article

Effect of C282Y genotype on self-reported musculoskeletal complications in hereditary hemochromatosis.

PloS one - 1 Jan 2015

Camacho António, Funck-Brentano Thomas, Simão Márcio, Cancela Leonor, Ottaviani Sébastien, Cohen-Solal Martine, Richette Pascal

Abstract excerpt

OBJECTIVE: Arthropathy that mimics osteoarthritis (OA) and osteoporosis (OP) is considered a complication of hereditary hemochromatosis (HH). We have limited data comparing OA and OP prevalence among HH patients with different hemochromatosis type 1 (HFE) genotypes. We investigated the prevalence of OA and OP in patients with HH by C282Y homozygosity and compound heterozygosity (C282Y/H63D) genotype. METHODS: A...

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Source

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Identifiers

PMID: 25822977
DOI: 10.1371/journal.pone.0122817
PMCID: PMC4378978

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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