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Article

Increased risk for colorectal adenomas and cancer in mono-allelic MUTYH mutation carriers: results from a cohort of North-African Jews.

Familial cancer - 1 Sept 2015

Rosner Guy, Bercovich Dani, Daniel Yael Etzion, Strul Hana, Fliss-Isakov Naomi, Ben-Yehoiada Meirav, Santo Erwin, Halpern Zamir, Kariv Revital

Abstract excerpt

Bi-allelic MUTYH gene mutations are associated with a clinical phenotype of multiple colorectal adenomas and an increased risk for colorectal cancer (CRC). It is unclear whether mono-allelic MUTYH gene carriers (heterozygotes) are also at increased risk for even few adenomas or cancer. In order to clarify an association between MUTYH heterozygotes and adenomas, we evaluated the frequency and types of MUTYH...

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Source

Identifiers

PMID: 25822476
DOI: 10.1007/s10689-015-9799-7

Genes

MUTYH
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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