Article
Common MUTYH mutations and colorectal cancer risk in multiethnic populations.
Familial cancer - 1 Sept 2012
Lejbkowicz Flavio, Cohen Ilana, Barnett-Griness Ofra, Pinchev Mila, Poynter Jen, Gruber Stephen B, Rennert Gad
Abstract excerpt
MUTYH is associated with colorectal cancer (CRC) risk. We studied the frequency of MUTYH and risk of CRC in Arabs, North African and European Jews. Participants were all 593 Sephardi Moroccan Jews (232 cases, 361 controls) and all 631 Arabs (327 cases, 304 controls) recruited into a population-based study of colorectal cancer in Israel, as well as a random sample of 189 Ashkenazi Jewish cases. Two MUTYH...
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