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Transmembrane 6 superfamily member 2 gene E167K variant impacts on steatosis and liver damage in chronic hepatitis C patients

29 Mar 2015

Abstract excerpt

UNLABELLED: Steatosis and inherited host factors influence liver damage progression in chronic hepatitis C (CHC). The transmembrane 6 superfamily member 2 (TM6SF2) gene E167K variant increases liver fat and risk of progressive steatohepatitis by interfering with lipoprotein secretion. Our aim was to determine whether the E167K variant affects histological severity of steatosis, necroinflammation, and fibrosis in...

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Share to Diabetes, Cardiovascular Risks, and Lipoproteins
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PMID: 25820484
DOI: 10.1002/hep.27811

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Related research

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Transmembrane 6 superfamily member 2 gene E167K variant impacts on steatosis and liver damage in chronic hepatitis C patientsPMID 25820484Read ↗

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