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Article

The impact of transmembrane 6 superfamily 2 (TM6SF2) rs58542926 on liver-related events in patients with advanced chronic liver disease.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Aug 2023

Balcar Lorenz, Scheiner Bernhard, Urheu Markus, Weinberger Patrick, Paternostro Rafael, Simbrunner Benedikt, Semmler Georg, Willheim Claudia, Pinter Matthias, Ferenci Peter, Trauner Michael, Reiberger Thomas, Stättermayer Albert Friedrich, Mandorfer Mattias

Abstract excerpt

BACKGROUND & AIMS: Genetic factors such as the transmembrane 6 superfamily 2 (TM6SF2) rs58542926 single nucleotide variant(SNV) modulate the susceptibility for (advanced) chronic liver disease ([A]CLD). However, the impact of this variant in patients who have already progressed to ACLD is unknown. METHODS: The association between TM6SF2-rs58542926 genotype and liver-related events was evaluated in 938 ACLD...

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Share to Carcinoma, Hepatocellular
Share to Hypertension, Portal
Share to Liver
Share to Liver Cirrhosis
Share to Liver Neoplasms
Share to Membrane Proteins
Share to Non-alcoholic Fatty Liver Disease
Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 36863929
DOI: 10.1016/j.dld.2023.02.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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