Article
Re-annotation of presumed noncoding disease/trait-associated genetic variants by integrative analyses.
Scientific reports - 30 Mar 2015
Chen Geng, Yu Dianke, Chen Jiwei, Cao Ruifang, Yang Juan, Wang Huan, Ji Xiangjun, Ning Baitang, Shi Tieliu
Abstract excerpt
Using RefSeq annotations, most disease/trait-associated genetic variants identified by genome-wide association studies (GWAS) appear to be located within intronic or intergenic regions, which makes it difficult to interpret their functions. We reassessed GWAS-Associated single-nucleotide polymorphisms (herein termed as GASs) for their potential functionalities using integrative approaches. 8834 of 9184 RefSeq...
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