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Article

A systematic approach to understand the functional consequences of non-protein coding risk regions.

Cell cycle (Georgetown, Tex.) - 15 Jan 2010

Coetzee Gerhard A, Jia Li, Frenkel Baruch, Henderson Brian E, Tanay Amos, Haiman Christopher A, Freedman Matthew L

Abstract excerpt

A primary goal of genetic association studies is to elucidate genes and novel biological mechanisms involved in disease. Recently, genome-wide association studies have identified many common genetic variants that are significantly associated with complex diseases such as cancer. In contrast to Mendelian disorders, a sizable fraction of the variants lies outside known protein-coding regions; therefore,...

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Identifiers

PMID: 20023379
DOI: 10.4161/cc.9.2.10419
PMCID: PMC3319348

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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