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Article

Demystifying non-coding GWAS variants: an overview of computational tools and methods.

Human molecular genetics - 20 Oct 2022

Schipper Marijn, Posthuma Danielle

Abstract excerpt

Genome-wide association studies (GWAS) have found the majority of disease-associated variants to be non-coding. Major efforts into the charting of the non-coding regulatory landscapes have allowed for the development of tools and methods which aim to aid in the identification of causal variants and their mechanism of action. In this review, we give an overview of current tools and methods for the analysis of...

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PMID: 35972862
DOI: 10.1093/hmg/ddac198
PMCID: PMC9585674

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