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Article

Extracellular vesicle–depleted fetal bovine and human sera have reduced capacity to support cell growth

1 Jan 2015

Abstract excerpt

BACKGROUND: Fetal bovine serum (FBS) is the most widely used serum supplement for mammalian cell culture. It supports cell growth by providing nutrients, growth signals, and protection from stress. Attempts to develop serum-free media that support cell expansion to the same extent as serum-supplemented media have not yet succeeded, suggesting that FBS contains one or more as-yet-undefined growth factors. One...

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PMID: 25819213
DOI: 10.3402/jev.v4.26373

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