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Identification of optimal conditions for human placental explant culture and extracellular vesicle release

26 Sept 2023

Abstract excerpt

Extracellular vesicles (EVs) can mediate intercellular communication, including signaling between the placenta and maternal tissues. Human placental explant culture is a versatile in vitro model system to investigate placental function. We performed systematic studies in different tissue culture media types and oxygen tensions to identify a defined serum-free culture condition that supports high trophoblast...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37829201
DOI: 10.1016/j.isci.2023.108046

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