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Article

SubmiRine: assessing variants in microRNA targets using clinical genomic data sets.

Nucleic acids research - 30 Apr 2015

Maxwell Evan K, Campbell Joshua D, Spira Avrum, Baxevanis Andreas D

Abstract excerpt

MicroRNAs (miRNAs) regulate gene expression by binding to partially complementary sequences on target mRNA transcripts, thereby causing their degradation, deadenylation, or inhibiting their translation. Genomic variants can alter miRNA regulation by modifying miRNA target sites, and multiple human disease phenotypes have been linked to such miRNA target site variants (miR-TSVs). However, systematic genome-wide...

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PMID: 25813044
DOI: 10.1093/nar/gkv256
PMCID: PMC4417167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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