miRTarDS: High-Accuracy Refining Protein-level MicroRNA Target Interactions from Prediction Databases Using Sentence-BERT

Abstract excerpt

MicroRNAs (miRNAs) regulate gene expression by binding to mRNAs, inhibiting translation, or promoting mRNA degradation. miRNAs are of great importance in the development of various diseases. Currently, numerous sequence-based miRNA target prediction tools are available, however, only 1% of their predictions have been experimentally validated. In this study, we propose a novel approach that leverages disease simila...

Topics

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• 3' Untranslated Regions
• Data Mining
• Databases, Nucleic Acid
• Exosomes
• Internet
• Molecular Sequence Annotation
• RNA, Untranslated
• User-Computer Interface

Identifiers and source

Literature Corpus work

44ff2328-978f-570e-8183-85175207ae73

DOI

10.1101/2024.05.17.594604