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Article

Complex Regulation of Human Neuronal Nitric-oxide Synthase Exon 1c Gene Transcription

1 Jul 2002

Abstract excerpt

Neuronal nitric-oxide synthase (nNOS) is expressed in a variety of human tissues and shows a complex transcriptional regulation with the presence of nine alternative first exons (1a-1i) resulting in nNOS transcripts with differing 5'-untranslated regions. We previously demonstrated that nNOS exon 1c, one of the predominant transcripts in the human gastrointestinal tract, is driven by a separate promoter (Saur,...

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PMID: 11960979
DOI: 10.1074/jbc.m109802200

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