Article
Mycobacterium tuberculosis-specific and MHC class I-restricted CD8+ T-cells exhibit a stem cell precursor-like phenotype in patients with active pulmonary tuberculosis.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Mar 2015
Axelsson-Robertson Rebecca, Ju Ji Hyeon, Kim Ho-Youn, Zumla Alimuddin, Maeurer Markus
Abstract excerpt
The nature and longevity of the T-cell response directed against Mycobacterium tuberculosis (MTB) are important for effective pathogen containment. We analyzed ex vivo the nature of MTB antigen-specific T-cell responses directed against the MTB secreted antigens Rv0288, Rv1886c, Rv3875, the antig...
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