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ARID5B rs10821936 and rs10994982 gene polymorphism and susceptibility to juvenile systemic lupus erythematosus and lupus nephritis.

Lupus - 1 Jul 2021

Mosaad Youssef M, Hammad Ayman, AlHarrass Mohamed F, Sallam Rehab, Shouma Amany, Hammad Enas, Ahmed Engy Osman, Abdel-Azeem Heba A, Sherif Doaa, Fawzy Iman, Elbahnasawy Amany, Abdel Twab Hosam

Abstract excerpt

BACKGROUND: The prevalence of SLE and the spectrum of clinical manifestations vary widely in different races and geographical populations. OBJECTIVE: To investigate the possible role of ARID5B rs10821936 and rs10994982 polymorphism as a risk factor for the development of SLE in children (jSLE) and to evaluate their role in relation to clinical manifestations especially lupus nephritis (LN). METHODS: DNA...

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PMID: 33888010
DOI: 10.1177/09612033211010338

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