Article
Interactions between environmental factors and melatonin receptor type 1A polymorphism in relation to oral cancer susceptibility and clinicopathologic development.
PloS one - 1 Jan 2015
Lin Feng-Yan, Lin Chiao-Wen, Yang Shun-Fa, Lee Wei-Jiunn, Lin Yung-Wei, Lee Liang-Ming, Chang Junn-Liang, Weng Wei-Chun, Lin Chien-Huang, Chien Ming-Hsien
Abstract excerpt
BACKGROUND: The purpose of this study was to explore the combined effect of melatonin receptor type 1A (MTNR1A) gene polymorphisms and exposure to environmental carcinogens on the susceptibility and clinicopathological characteristics of oral cancer. METHODOLOGY AND PRINCIPAL FINDINGS: Three polymorphisms of the MTNR1A gene from 618 patients with oral cancer and 560 non-cancer controls were analyzed by real-time...
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