Article
Mutant allele tumor heterogeneity (MATH) and head and neck squamous cell carcinoma.
Head and neck pathology - 1 Mar 2015
Rocco James W
Abstract excerpt
Intra-tumor heterogeneity, variation between individual tumor cells within a patient's tumor, is increasingly seen as a critical mechanism underlying treatment resistance and therapeutic failure. Despite this growing awareness, few methods to assess intra-tumor heterogeneity exist outside the research laboratory, especially in the absence of a known marker. Mutant allele tumor heterogeneity (MATH) is a novel,...
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