Genetic Association Between KIBRA Polymorphism and Alzheimer's Disease with in a Japanese Population.

doi:10.1007/s12017-015-8348-8

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Article

Genetic Association Between KIBRA Polymorphism and Alzheimer's Disease with in a Japanese Population.

Neuromolecular medicine - 1 Jun 2015

Kawai Eri, Shibata Nobuto, Nagata Tomoyuki, Shinagawa Shunichiro, Tagai Kenji, Tgai Kenji, Ohnuma Tohru, Shimazaki Hiromi, Toda Aiko, Kasanuki Koji, Takayama Toshiki, Suzuki Ayako, Nakayama Kazuhiko, Yamada Hisashi, Arai Heii

Abstract excerpt

KIBRA plays an important role in synaptic plasticity in human hippocampus related to cognitive function. Functional studies suggest that KIBRA is a potential candidate gene for memory and Alzheimer's disease (AD) risk. A single nucleotide polymorphism, Rs17070145 C allele affects the onset of AD in an age-dependent manner comparing with T/T genotypes and is also associated with risk of substance abuse and...

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PMID: 25800888
DOI: 10.1007/s12017-015-8348-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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