Article
Is KIBRA polymorphism associated with memory performance and cognitive impairment in Alzheimer's disease?
Journal of Alzheimer's disease : JAD - 1 Nov 2024
Jurasova Vanesa, Andel Ross, Katonova Alzbeta, Nolan Raena, Lacinova Zuzana, Kolarova Tereza, Matoska Vaclav, Vyhnalek Martin, Hort Jakub
Abstract excerpt
BACKGROUND: Genetic variations in a common single nucleotide polymorphism in the ninth intron of the KIBRA gene have been linked to memory performance and risk of Alzheimer's disease (AD). OBJECTIVE: We examined the risk of AD related to presence of KIBRA T allele (versus CC homozygote) and to memory performance. The role of established genetic risk factors APOE ε4 and BDNF Met was also considered. METHODS:...
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