Article
SNP marker discovery in koala TLR genes.
PloS one - 1 Jan 2015
Cui Jian, Frankham Greta J, Johnson Rebecca N, Polkinghorne Adam, Timms Peter, O'Meally Denis, Cheng Yuanyuan, Belov Katherine
Abstract excerpt
Toll-like receptors (TLRs) play a crucial role in the early defence against invading pathogens, yet our understanding of TLRs in marsupial immunity is limited. Here, we describe the characterisation of nine TLRs from a koala immune tissue transcriptome and one TLR from a draft sequence of the koala genome and the subsequent development of an assay to study genetic diversity in these genes. We surveyed genetic...
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