Article
Investigation into the genetic diversity in toll-like receptors 2 and 4 in the European badger Meles meles.
Research in veterinary science - 1 Aug 2018
Whiteoak Andrew M, Ideozu Justin, Alkathiry Hadil, Tomlinson Alexandra J, Delahay Richard J, Cowen Sara, Mullineaux Elizabeth, Gormley Eamonn, Birtles Richard J, Lun Zhao-Rong, Hide Geoff
Abstract excerpt
The Toll-like receptor (TLR) genes are a conserved family of genes central to the innate immune response to pathogen infection. They encode receptor proteins, recognise pathogen associated molecular patterns (PAMPs) and trigger initial immune responses. In some host-pathogen systems, it is reported that genetic differences, such as single nucleotide polymorphisms (SNPs), associate with disease resistance or...
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