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Article

Quantitative defects in invariant NKT cells and TLR responses in patients with hyper-IgE syndrome.

Allergologia et immunopathologia - 1 Jan 2000

Gutierrez-Hincapié S, Muskus-López C E, Montoya C J, Trujillo-Vargas C M

Abstract excerpt

BACKGROUND: Autosomal dominant hyper-IgE syndrome (AD-HIES) is a primary immunodeficiency mainly caused by mutations in STAT3, a signalling molecule implicated in the development of appropriate immune responses. We aimed to characterise the innate immune response in AD-HIES. METHODS: The frequency of innate immune cells in peripheral blood (PB) from seven AD-HIES patients and healthy controls were determined....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25796310
DOI: 10.1016/j.aller.2014.11.002

Genes

STAT3
LTA
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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