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Article

Dose-dependent regulation of horizontal cell fate by Onecut family of transcription factors.

PloS one - 1 Jan 2020

Kreplova Michaela, Kuzelova Andrea, Antosova Barbora, Zilova Lucie, Jägle Herbert, Kozmik Zbynek

Abstract excerpt

Genome duplication leads to an emergence of gene paralogs that are essentially free to undergo the process of neofunctionalization, subfunctionalization or degeneration (gene loss). Onecut1 (Oc1) and Onecut2 (Oc2) transcription factors, encoded by paralogous genes in mammals, are expressed in precursors of horizontal cells (HCs), retinal ganglion cells and cone photoreceptors. Previous studies have shown that...

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Identifiers

PMID: 32790713
DOI: 10.1371/journal.pone.0237403
PMCID: PMC7425962

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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