Article
Suppression of sensitivity to drugs and antibiotics by high external cation concentrations in fission yeast.
PloS one - 1 Jan 2015
Alao John P, Weber Andrea M, Shabro Aidin, Sunnerhagen Per
Abstract excerpt
BACKGROUND: Potassium ion homeostasis plays an important role in regulating membrane potential and therefore resistance to cations, antibiotics and chemotherapeutic agents in Schizosaccharomyces pombe and other yeasts. However, the precise relationship between drug resistance in S. pombe and external potassium concentrations (particularly in its natural habitats) remains unclear. S. pombe can tolerate a wide...
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