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Article

Evidence of long-lived founder virus in mother-to-child HIV transmission.

PloS one - 1 Jan 2015

Danaviah Sivapragashini, de Oliveira Tulio, Bland Ruth, Viljoen Johannes, Pillay Sureshnee, Tuaillon Edouard, Van de Perre Philippe, Newell Marie-Louise

Abstract excerpt

Exposure of the infant's gut to cell-associated and cell-free HIV-1 trafficking in breast milk (BM) remains a primary cause of mother-to-child transmission (MTCT). The mammary gland represents a unique environment for HIV-1 replication and host-virus interplay. We aimed to explore the origin of the virus transmitted during breastfeeding, and the link with quasi-species found in acellular and cellular fractions of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25793402
DOI: 10.1371/journal.pone.0120389
PMCID: PMC4368793

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