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Origin of the Transmitted Virus in HIV Infection: Infected Cells Versus Cell-Free Virus

20 Nov 2014

Abstract excerpt

All human immunodeficiency virus type 1 (HIV-1)-infected inocula, such as genital secretions, breast milk, and blood, contain both cell-free virus and infected cells. The relative contributions of cell-free and/or cell-associated virus in establishing an infection in a naive host during the different modes of HIV-1 acquisition remains unclear. Studies aim to elucidate the source of the acquired virus because...

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PMID: 25414422
DOI: 10.1093/infdis/jiu369

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