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Increased DNA methylation of the SLC30A8 gene promoter is associated with type 2 diabetes in a Malay population

17 Mar 2015

Abstract excerpt

BACKGROUND: Recent studies have demonstrated that DNA polymorphisms in the solute carrier family 30 member 8 (SLC30A8) gene confer the risk susceptibility to type 2 diabetes (T2D). The present study aimed to analyze DNA methylation levels of this gene in T2D and diabetic nephropathy (DN). RESULTS: We confirmed the genetic association study of SLC30A8 in 992 Malay subjects with normal glucose tolerance and T2D...

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Share to Chronic Kidney Disease and Diabetes
Share to Epigenetics and DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25793017
DOI: 10.1186/s13148-015-0049-5

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