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Article

Expression of Specificity Protein Transcription Factors in Pancreatic Cancer and their Association in Prognosis and Therapy

1 Jun 2012

Abstract excerpt

Pancreatic cancer is an aggressive malignancy with poor prognosis. Pancreatic adenocarcinoma is one of the leading causes of cancer-related deaths in the United States. Due to the aggressive nature of this malignancy, there is a serious concern for identifying effective targets, and adopting novel strategies for therapy. Members of the Specificity Protein (Sp) family of transcription factors, Sp1, Sp3, and Sp4...

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PMID: 22725697
DOI: 10.2174/092986712801661077

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