Article
Regulation of a protein synthesis initiation factor by adenovirus virus-associated RNA.
Nature - 1 Jan 2000
Reichel P A, Merrick W C, Siekierka J, Mathews M B
Abstract excerpt
A small RNA accumulating late in adenovirus infection is required for efficient protein synthesis, although not specifically for the translation of viral proteins. This RNA maintains the activity of an initiation factor catalysing the earliest step of polypeptide chain initiation.
Topics
- Antigens
- Autoantigens
- Cytoplasm
- Eukaryotic Initiation Factor-2
- Female
- HeLa Cells
- Humans
- Mutation
- Peptide Chain Initiation, Translational
- Peptide Initiation Factors
- Proteins
- RNA
- RNA, Small Nuclear