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Article

The 5'UTR in human adenoviruses: leader diversity in late gene expression.

Scientific reports - 4 Apr 2017

Ramke Mirja, Lee Jeong Yoon, Dyer David W, Seto Donald, Rajaiya Jaya, Chodosh James

Abstract excerpt

Human adenoviruses (HAdVs) shut down host cellular cap-dependent mRNA translation while initiating the translation of viral late mRNAs in a cap-independent manner. HAdV 5' untranslated regions (5'UTRs) are crucial for cap-independent initiation, and influence mRNA localization and stability. However, HAdV translational regulation remains relatively uncharacterized. The HAdV tripartite leader (TPL), composed of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 28377580
DOI: 10.1038/s41598-017-00747-y
PMCID: PMC5429599

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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