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Article

The PPARγ2 Pro12Ala variant is protective against progression of nephropathy in people with type 2 diabetes.

Journal of translational medicine - 12 Mar 2015

Lapice Emanuela, Monticelli Antonella, Cocozza Sergio, Pinelli Michele, Cocozza Sara, Bruzzese Dario, Riccardi Gabriele, Vaccaro Olga

Abstract excerpt

OBJECTIVE: Cross-sectional studies suggest the association between diabetic nephropathy and the PPARγ2 Pro12Ala polymorphism of the peroxisome proliferator-activated receptor γ2 (PPARγ2). Prospective data are limited to microalbuminuria and no information on renal function is available to date. The present study evaluates the association between the Pro12Ala polymorphism of PPARγ2 and the progression of...

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Share to Diabetes Mellitus, Type 2
Share to Diabetic Nephropathies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 25889595
DOI: 10.1186/s12967-015-0448-6
PMCID: PMC4358785

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