Article
Peroxisome proliferator-activated receptor γ polymorphism Pro12Ala Is associated with nephropathy in type 2 diabetes: evidence from meta-analysis of 18 studies.
Diabetes care - 1 Jun 2012
Zhang Hui, Zhu Shimiao, Chen Jing, Tang Yang, Hu Hailong, Mohan Viswanathan, Venkatesan Radha, Wang Jianmin, Chen Haiping
Abstract excerpt
OBJECTIVE: Insulin resistance plays a part in diabetic nephropathy (DN). The association between the peroxisome proliferator-activated receptor γ Pro to Ala alteration at codon 12 (Pro12Ala) polymorphism and the risk of insulin resistance has been confirmed. The association between the polymorphism and DN risk has also been widely studied recently, but no consensus was available up to now. RESEARCH DESIGN AND...
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