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Article

Tumor profiling of gastric and esophageal carcinoma reveal different treatment options.

Cancer biology & therapy - 1 Jan 2015

Miura John T, Xiu Joanne, Thomas James, George Ben, Carron Benjamin R, Tsai Susan, Johnston Fabian M, Turaga Kiran K, Gamblin T Clark

Abstract excerpt

BACKGROUND: NCCN states that chemotherapies for advanced esophageal and gastric cancers may be used interchangeably. Biomarkers from gastroesophageal cancer patients were interrogated to identify actionable alterations with therapeutic implications. METHODS: 666 gastric and 640 esophageal cancer cases referred to Caris Life Sciences between 2009 thru 2013 were evaluated. Specific testing was performed, which...

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Identifiers

PMID: 25778705
DOI: 10.1080/15384047.2015.1026479
PMCID: PMC4622996

Genes

ERCC1
RRM1
SPARC
APC
KRAS
MGMT
SMAD4

Provenance

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