Article
Translating genomic profiling to gastrointestinal cancer treatment.
Future oncology (London, England) - 1 Apr 2017
Harada Kazuto, Mizrak Kaya Dilsa, Shimodaira Yusuke, Song Shumei, Baba Hideo, Ajani Jaffer A
Abstract excerpt
Next-generation sequencing enables faster, cheaper and more accurate whole-genome sequencing, allowing genome profiling and discovery of molecular features. As molecular targeted drugs are developed, treatment can be tailored according to molecular subtype. Gastric and colorectal cancers have each been divided into four subtypes according to molecular features. Profiling of the esophageal cancer genome is...
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