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Translating gastric cancer genomics into targeted therapies

20 Feb 2016

Abstract excerpt

Gastric cancer is a common disease with limited treatment options and a poor prognosis. Many gastric cancers harbour potentially actionable targets, including over-expression and mutations in tyrosine kinase pathways. Agents have been developed against these targets with varying success- in particular, the use of trastuzumab in HER2-overexpressing gastric cancers has resulted in overall survival benefits. Gastric...

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PMID: 26947813
DOI: 10.1016/j.critrevonc.2016.02.007

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