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Article

Stomatin-like protein 2 is required for in vivo mitochondrial respiratory chain supercomplex formation and optimal cell function.

Molecular and cellular biology - 1 May 2015

Mitsopoulos Panagiotis, Chang Yu-Han, Wai Timothy, König Tim, Dunn Stanley D, Langer Thomas, Madrenas Joaquín

Abstract excerpt

Stomatin-like protein 2 (SLP-2) is a mainly mitochondrial protein that is widely expressed and is highly conserved across evolution. We have previously shown that SLP-2 binds the mitochondrial lipid cardiolipin and interacts with prohibitin-1 and -2 to form specialized membrane microdomains in the mitochondrial inner membrane, which are associated with optimal mitochondrial respiration. To determine how SLP-2...

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Identifiers

PMID: 25776552
DOI: 10.1128/MCB.00047-15
PMCID: PMC4405640

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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