Article
Oseltamivir expands quasispecies of influenza virus through cell-to-cell transmission.
Scientific reports - 16 Mar 2015
Mori Kotaro, Murano Kensaku, Ohniwa Ryosuke L, Kawaguchi Atsushi, Nagata Kyosuke
Abstract excerpt
The population of influenza virus consists of a huge variety of variants, called quasispecies, due to error-prone replication. Previously, we reported that progeny virions of influenza virus become infected to adjacent cells via cell-to-cell transmission pathway in the presence of oseltamivir. During cell-to-cell transmission, viruses become infected to adjacent cells at high multiplicity since progeny virions...
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