Article
A common genetic variation in the promoter of miR-107 is associated with gastric adenocarcinoma susceptibility and survival.
Mutation research - 1 Nov 2014
Wang Shizhi, Lv Chunye, Jin Hua, Xu Ming, Kang Meiyun, Chu Haiyan, Tong Na, Wu Dongmei, Zhu Haixia, Gong Weida, Zhao Qinghong, Tao Guoquan, Zhou Jianwei, Zhang Zhengdong, Wang Meilin
Abstract excerpt
BACKGROUND: Global miRNA expression profile has been widely used to characterize human cancers. It is well established that genetic variants in miRNAs can modulate miRNA biogenesis and disease risk. METHODS: Genome-wide miRNA microarray was employed for assessment of miRNA expression profile of gastric adenocarcinoma (GAC). The variants of significantly dysregulated miRNA were genotyped in test (715 cases and 804...
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